S/N

LECTURE TOPIC

Duration(Hours)

1.

Introduction to Pathology: comparing the ancient, traditional and modern concept of microscopic and ultramicroscopic changes following cellular injury including necrosis. Reversibility and irreversibility of cellular changes.

3

2.

Apoptosis and underlying mechanism

1

3.

Mechanism underlying intracellular accumulation of substances and the consequence. Pigments and its importance. Abnormal calcifications.

           3

4.

Adaptation of cells to various insults Aging of cells and the underlying mechanism.

           1

5.

Acute inflammation; vascular changes, cellular events.

2

6.

Role of chemical mediators in inflammation, cells of chronic inflammation.

1

7.

Chronic inflammation, events cells of chronic inflammation.

           1

8.

Immunity and disorders; of the immune system, hypersensitivity reaction.

            5

9.

Transplant rejection, autoimmune reaction

Immunological deficiency syndromes (primary and acquired), amyloidosis,

            5

10.

Fluid and haemodynamics; oedema, Hyperaemia, congestion, haemorrhage

Embolism, shock, infarction

            6

11.

Genetic disorders; Mendelian disorders

            3

12.

Disorders with multifactorial inheritance

Cytogenetic disorders, molecular diagnosis

            3

13

Neoplasia, Characteristics of Benign and malignant neoplasms

1

14.

Molecular basis of cancer, biology of tumour growth

           3

15.

Carcinogenic agents and their cellular interactions (chemical, radiation, viral and microbial agents), tumor immunity

           3

16.

Infectious diseases; transmission and dissemination of microbes

          3

17.

Infectious diseases peculiar to the tropics – including pathology of malaria,typhoid, cholera etc

          3

18.

Respiratory infections, GIT infections, sexually transmitted diseases

          4

19.

Environmental and nutritional diseases; Occupational and environmental exposures

          2

20.

Protein energy malnutrition, obesity and diseases

           1

21.

Vitamin deficiency and disease

1

22.

Diseases of infancy and childhood; malformations, inborn errors of metabolism

           3

23.

Tumours peculiar to infancy

2

TOTAL NUMBER OF HOURS

60

S/N

LECTURE TOPIC

DURATION(HOURS)

1.

The gastrointestinal system; congential anomalies of the oesophagus, tumours of the oesophagus, malabsorption syndrome, etc

Peptic ulcer disease, infectious disease of the GIT.

             6

2.

Disease of the large and small intestine

Diseases of the liver and biliary tract; hepatitis, jaundice and causes, Diseases of exocrine pancreas.

6

3.

Cirrhosis, inborn errors of metabolism as it affect the liver

Hepatic biliary tract disease, tumours, Cholecystitis and cholelithiasis

8

4.

Lympho reticular system

6

5.

Vascular disorders, response of blood vessel to injury, atherosclerosis.

Hypertensive vascular disease, etc

4

Diseases of the Heart, congenital heart disease, heart failure, ischaemic heart disease. Disease of the endocardium.

Myocardial disease, diseases of the pericardium, etc

6

6.

7.

Diseases of the kidney; Pathophysiology of renal diseases, cystic diseases of the kidney, interstitial diseases of the kidney.

Glomerular diseases – glomerulonephritis

10

8.

Acute renal failure, ATN

Chronic renal failure, Renal changes in hypertension

8

9.

The Central nervous system and diseases – introduction, Reactions of the Nervous system to disease, Expanding lesions, hydrocephalus

4

10.

The Central nervous system and diseases – head injury including fracture and brain and spinal cord damage, infections of the nervous system

6

11.

Infectious disease of the nervous system

Tumours of the nervous system and diseases of the spinal cord

8

12.

The endocrine system; pituitary gland and its disorders, adrenal gland and its disorders, MEN Syndrome.

6

13.

The endocrine system; thyroid gland – simple goiter, hypothyroidism, Hashimoto thyroiditis and hyperthyroidism, Grave’s disease.

The endocrine system; diseases of endocrine pancreas; diabetes mellitus

8

14.

Respiratory diseases; obstructive and restrictive pulmonary disease.

Interstitial pulmonary disease.

6

15.

Infectious disease of the lungs and respiratory passages

Diseases of the pleura, tumours

8

16.

The skin and diseases, Hereditary and congenital condition, virus diseases of the skin,  inflammatory conditions of the skin

4

17.

The skin and diseases – Vascular diseases of the skin, connective tissue diseases, granulomatous diseases

Tumours of the skin

4

18

The female genital system including ovarian diseases

Diseases of the breast; infectious disease, tumours in Female & Male

8

19.

The male genital system including the testes, tumours

8

TOTAL IN HOURS

124